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Board

John Sclater, CVO (Chairman) *†#

John Sclater, aged 70, has served on the Board as Chairman since the launch of the Company in June 1997; he is also Chairman of the Nominations Committee. He was formerly a Trustee of The Grosvenor Estate, Chairman of Hill Samuel Bank Limited, Chairman of Foreign & Colonial Investment Trust PLC, Chairman of Graphite Enterprise Trust PLC, First Church Estates Commissioner, President of The Equitable Life Assurance Society and a Director of other public companies. He remains a self-employed farmer and Chairman of Argent Group (Europe) Ltd and of Burner, Nicol & Co. Limited.

Sven Borho

Sven Borho, aged 44, joined the Board in March 2006. He is a founding General Partner of OrbiMed Capital LLC, the Company’s Investment Manager, where he acts as a portfolio manager for OrbiMed’s public equity funds and heads the firm’s trading activities. He started his career in 1991 when he joined Mehta and Isaly as a Senior Analyst covering European pharmaceutical firms and biotechnology companies worldwide. Sven studied business administration at Bayreuth University in Germany and received an M.Sc (Econ.) from The London School of Economics.

Paul Gaunt †#

Paul Gaunt, aged 62, joined the Board in June 1997. Paul is self-employed and has over 30 years’ experience in the investment industry. He was formerly Senior Investment Manager and an Assistant General Manager of The Equitable Life Assurance Society and a Director of Brit Insurance Holdings PLC and of Oasis Healthcare plc. Paul is a Director of RCM Technology Trust PLC.

Dr John Gordon *†#

Dr John Gordon, aged 66, joined the Board in June 1997 and has been designated as the Senior Independent Director; he is also Chairman of the Remuneration Committee. Dr Gordon is Chairman of, and employed by, Quercus Management Limited and has previously acted as Director of several biotechnology companies, as well as working at Beecham Research Laboratories, Cambridge University and the Medical Research Council.

Peter Keen *†#

Peter Keen, aged 53, has served on the Board as a Director since the launch of the Company in June 1997 and is Chairman of the Audit & Management Engagement Committee. A chartered accountant, he has over 25 years’ experience in the management and financing of biotechnology businesses and up until March 2010 was the Corporate Development and Finance Director of the privately held biopharmaceutical company Serentis Limited. He has served as a Director of a number of technology businesses and is currently the Senior Independent Director of Abcam plc, a Director of Ark Therapeutics Group plc and Chairman of Oval Medical Technologies Limited and of Exosect Limited.

The Rt Hon Lord Waldegrave of North Hill *†#

Lord Waldegrave of North Hill, aged 64, joined the Board in June 1998. He is Provost of Eton College and acts as a consultant to investment bank UBS, where he was formerly Vice-Chairman of their Investment Banking Department. He is a Director of Fleming Family & Partners Limited and was previously Chairman of the Global Financial Institutions Group at Dresdner Kleinwort Wasserstein. From 1979 to 1997, he was MP for Bristol West holding a number of Cabinet posts including Secretary of State for Health. Lord Waldegrave of North Hill is also Chairman of the Rhodes Trust.

* Member of the Audit and Management Engagement Committee
† Member of the Nominations Committee
# Member of the Remuneration Committee